2021 Discussion Meetings

Prof. Uwe Tauber (Physics, Virginia Tech)

"Writing useful referee reports and helpful responses"

Slides: "Juan-Jose Lietor-Santos, Physical Review E (2020)"

Host: Vinh Nguyen

Ranit Mukherjee (Mechanical Engineering, Virginia Tech)

"To Jump, or not to Jump, that is the Question"

Host: Vinh Nguyen

James Stidham (Physics, Virginia Tech)

"Magnetic Skyrmion Motion in a Channel"

Host: Vinh Nguyen

Dr. Sudipta Gupta (Physics, Virginia Tech)

"A Scattering Approach to Self-Assembled BioSoft Materials"

Host: Vinh Nguyen

Yisheng Huang (Physics, Virginia Tech)

"Chain Conformations and Phase Separations in Polymer Solutions at Various Polymer-Solvent Interactions"

Host: Vinh Nguyen

No Discussion Meeting

Host:

Dr. James McClure (Advanced Research Computing, Virginia Tech)

"Digital Scavenger Hunt: is the geometry of complex micro-structure unique?"

Host: Vinh Nguyen

Prof. Uwe Tauber (Physics, Virginia Tech)

"How to Write a Paper"

Host: Vinh Nguyen

Sean McMahon (Physics, Virginia Tech)

"Mechanical Limitations of Clostridium Perfringens Chains"

Host: Vinh Nguyen

Navid Ghaffarzadegan ( Industrial and Systems Engineering, Virginia Tech)

"Epidemic Forecasting: Why Did Most COVID-19 Models Fail"

Host: Vinh Nguyen

Ruslan Mukhamadiarov (Physics, Virginia Tech)

"Critical Dynamics of the Susceptible-Infectious-Recovered (SIR) Model on a Lattice"

Host: Vinh Nguyen

Dr. Johannes Zierenberg (Max Planck Institute for Dynamics and Self-Organization, Gottingen and Georg August University )

"Temporal resonance between disease progression and contact patterns shapes epidemic spread"

Host: Vinh Nguyen

Yifei Wang (Physics, Virginia Tech)

"Graphene Mid-infrared Photodetectors Based on Blocked Silicon Impurity Bands"

Host: Vinh Nguyen

Teshani Kumarage (Physics, Virginia Tech)

"Biophysical effects of Melatonin and Azithromycin on Model Pulmonary Membranes"

Host: Vinh Nguyen

Ronald Dickman (Universidade Federal de Minas Gerais, Brazil)

“Phase Diagram and Interfacial Instabilities in the Driven Widom-Rowlinson Lattice Gas”

Host: Vinh Nguyen

No Discussion Meeting

Host: Vinh Nguyen

No Discussion Meeting

Host: Vinh Nguyen

Wenya Shu (Physics, Virginia Tech)

“A Bio-chemo-mechanical Multiscale Theory for Mechanosensitive Cell Migration on the Viscoelastic Substrate”

Increasing experimental evidence validates that both the elastic rigidity and viscosity of the extracellular matrix (ECM) significantly affect the mode and rate of cell motility. As for the effect of rigidity, malignant cells rationally switch between durotaxis (migration to stiffer regions) and negative durotaxis (migration to softer regions) during metastasis inside biological tissues. Meanwhile, medium viscosity can modulate the effect of elasticity on cell behaviors. To investigate the mechano-sensing of a mesenchymal cell on a viscoelastic substrate, we formulated a multi-scale bio-chemo-mechanical model for the modeling of a whole cell. The proposed framework takes into account the feedback between the biochemical and bio-mechanical events and integrates the motor-clutch model at the sub-cellular scale with the cell structural analysis at the global level. Our simulated single cell (i) yields a biphasic migration speed profile in response to the ECM stiffness; (ii) can exhibit both durotaxis and negative durotaxis, in either case migrating toward the region with an optimal stiffness from softer and stiffer regions, respectively; (iii) reveals that high viscosity can give rise to cellular migration toward softer regions, preempting stiffness-induced durotaxis. Overall, these findings provide non-trivial new insights into the role of viscosity in durotaxis and pave the way for designing bio-materials that optimize cell migration behaviors.

Host: Vinh Nguyen

No Discussion Meeting

Host: Vinh Nguyen

No Discussion Meeting

Host: Vinh Nguyen

Junwen Wang (Physics, Virginia Tech)

"An Analytic Form of the Integrated Lennard-Jones Potential for Thin Rods”

Host: Vinh Nguyen